{"id":905,"date":"2024-01-14T19:15:09","date_gmt":"2024-01-14T17:15:09","guid":{"rendered":"https:\/\/ausis.uniovi.es\/?page_id=905"},"modified":"2024-01-17T11:58:20","modified_gmt":"2024-01-17T09:58:20","slug":"projects","status":"publish","type":"page","link":"https:\/\/ausis.uniovi.es\/?page_id=905&lang=en","title":{"rendered":"Projects"},"content":{"rendered":"\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h1 class=\"wp-block-heading has-text-align-center\">Our projects<\/h1>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-cover alignfull is-light\" style=\"min-height:600px;aspect-ratio:unset;\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-neve-link-color-background-color has-background-dim-100 has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<div class=\"wp-block-group has-neve-link-color-background-color has-background\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<h2 class=\"wp-block-heading has-text-align-center has-neve-text-color-color has-text-color\">Autophagy and cancer<\/h2>\n\n\n\n<div class=\"wp-block-columns are-vertically-aligned-center is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<p class=\"has-text-align-center has-medium-font-size wp-block-paragraph\">Autophagy helps cells survive. Paradoxically, this implies that it can both prevent the appearance of tumours (protecting healthy cells) and contribute to their progression (supporting cancer cells).<\/p>\n\n\n\n<p class=\"has-text-align-center has-medium-font-size wp-block-paragraph\">Therefore, it is necessary to determine in which contexts it is interesting to promote or block the route.<\/p>\n\n\n\n<p class=\"has-text-align-center has-medium-font-size wp-block-paragraph\">This is one of the objectives of AU\u00b7SIS, <strong>identifying new autophagic markers in cancer<\/strong> so we can improve diagnosis and treatment in oncology.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\"><div class=\"wp-block-image size-large is-style-rounded\">\n<figure class=\"aligncenter size-full is-resized has-custom-border\"><img loading=\"lazy\" decoding=\"async\" width=\"512\" height=\"512\" src=\"https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/cropped-Ico-Autofagosoma.png\" alt=\"\" class=\"wp-image-373\" style=\"border-style:none;border-width:0px;border-radius:50px;width:410px;height:auto\" srcset=\"https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/cropped-Ico-Autofagosoma.png 512w, https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/cropped-Ico-Autofagosoma-300x300.png 300w, https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/cropped-Ico-Autofagosoma-150x150.png 150w, https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/cropped-Ico-Autofagosoma-270x270.png 270w, https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/cropped-Ico-Autofagosoma-192x192.png 192w, https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/cropped-Ico-Autofagosoma-180x180.png 180w, https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/cropped-Ico-Autofagosoma-32x32.png 32w\" sizes=\"auto, (max-width: 512px) 100vw, 512px\" \/><\/figure>\n<\/div>\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-cover alignfull is-light\" style=\"min-height:600px;aspect-ratio:unset;\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-nv-light-bg-background-color has-background-dim-100 has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<div class=\"wp-block-group has-nv-light-bg-background-color has-background\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div style=\"height:80px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-neve-text-color-color has-text-color\">Autosis<\/h2>\n\n\n\n<div class=\"wp-block-columns are-vertically-aligned-center is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<p class=\"has-text-align-center has-medium-font-size wp-block-paragraph\">Autosis is a type of cell death highly dependent on autophagy and the Na+\/K+-ATPase pump.<\/p>\n\n\n\n<p class=\"has-text-align-center has-medium-font-size wp-block-paragraph\">Described in 2013, it has been found in pathologies such as ischemia or anorexia nervosa. However, we still do not know its molecular mechanisms.<\/p>\n\n\n\n<p class=\"has-text-align-center has-medium-font-size wp-block-paragraph\">Therefore, one of the main objectives of AU\u00b7SIS is the <strong>molecular characterization of autosis<\/strong>, so we can better understand its causes and regulation, and apply this new knowledge in the clinic.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\"><div class=\"wp-block-image size-large is-style-rounded\">\n<figure class=\"aligncenter size-full is-resized has-custom-border\" id=\"wp-block-themeisle-blocks-image-fa065419\"><img loading=\"lazy\" decoding=\"async\" width=\"1782\" height=\"1782\" src=\"https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/Autotic-cell.png\" alt=\"\" class=\"wp-image-522\" style=\"border-style:none;border-width:0px;border-radius:50px;width:410px;height:auto\" srcset=\"https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/Autotic-cell.png 1782w, https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/Autotic-cell-300x300.png 300w, https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/Autotic-cell-1024x1024.png 1024w, https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/Autotic-cell-150x150.png 150w, https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/Autotic-cell-768x768.png 768w, https:\/\/ausis.uniovi.es\/wp-content\/uploads\/2023\/07\/Autotic-cell-1536x1536.png 1536w\" sizes=\"auto, (max-width: 1782px) 100vw, 1782px\" \/><\/figure>\n<\/div>\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-cover alignfull is-light has-neve-text-color-color has-text-color has-link-color wp-elements-9277c2e937787f4ddb550e0b67e55466\" style=\"min-height:300px;aspect-ratio:unset;\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-neve-text-color-background-color has-background-dim-100 has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<div style=\"height:140px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-nv-text-dark-bg-color has-text-color has-large-font-size\">Let&#8217;s collaborate!<\/h2>\n\n\n\n<p class=\"has-text-align-center has-nv-text-dark-bg-color has-neve-text-color-background-color has-text-color has-background has-link-color has-medium-font-size wp-elements-bd5891ec6db04c30b2173bf0d387c280 wp-block-paragraph\">If your research group is interested in collaborating with AU\u00b7SIS for any autophagy and\/or autosis project, get in touch! It will be a pleasure to work together to advance these fields of research.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-fe48e5de wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-font-size is-style-secondary has-medium-font-size\"><a class=\"wp-block-button__link has-neve-link-hover-color-background-color has-background wp-element-button\" href=\"https:\/\/ausis.uniovi.es\/?page_id=969&amp;lang=en\">Contact us!<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:140px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Our projects<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"on","neve_meta_content_width":100,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"on","_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-905","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/ausis.uniovi.es\/index.php?rest_route=\/wp\/v2\/pages\/905","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ausis.uniovi.es\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ausis.uniovi.es\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ausis.uniovi.es\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ausis.uniovi.es\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=905"}],"version-history":[{"count":20,"href":"https:\/\/ausis.uniovi.es\/index.php?rest_route=\/wp\/v2\/pages\/905\/revisions"}],"predecessor-version":[{"id":1011,"href":"https:\/\/ausis.uniovi.es\/index.php?rest_route=\/wp\/v2\/pages\/905\/revisions\/1011"}],"wp:attachment":[{"href":"https:\/\/ausis.uniovi.es\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=905"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}