Our projects
Autophagy and cancer
Autophagy helps cells survive. Paradoxically, this implies that it can both prevent the appearance of tumours (protecting healthy cells) and contribute to their progression (supporting cancer cells).
Therefore, it is necessary to determine in which contexts it is interesting to promote or block the route.
This is one of the objectives of AU·SIS, identifying new autophagic markers in cancer so we can improve diagnosis and treatment in oncology.
Autosis
Autosis is a type of cell death highly dependent on autophagy and the Na+/K+-ATPase pump.
Described in 2013, it has been found in pathologies such as ischemia or anorexia nervosa. However, we still do not know its molecular mechanisms.
Therefore, one of the main objectives of AU·SIS is the molecular characterization of autosis, so we can better understand its causes and regulation, and apply this new knowledge in the clinic.
Let’s collaborate!
If your research group is interested in collaborating with AU·SIS for any autophagy and/or autosis project, get in touch! It will be a pleasure to work together to advance these fields of research.